Area of Research
Dissolution and In-Vitro Release Testing
Dissolution testing measures the rate and extent to which an active pharmaceutical ingredient is released from a solid oral dosage form into solution under standardised experimental conditions, and serves as a critical quality control tool and a surrogate predictor of in vivo drug absorption. This chapter examines the compendial dissolution apparatus, the principles governing dissolution method development, the biopharmaceutics classification system, and the concept of in vitro-in vivo correlation.
Chapter overview
The compendial dissolution apparatus, dissolution method development, and the biopharmaceutics classification system together with in vitro-in vivo correlation.
